NAD+ Therapy · Does It Work · Serving Leesburg
NAD+ Therapy for Leesburg, FL
"Does NAD therapy work?" is the question every page selling it should answer first and almost none does. The honest answer has three parts. NAD+, the coenzyme every cell uses to turn food into energy and to repair itself, genuinely declines with age; that is settled. Raising it is genuinely possible; the trials show that too. Whether raising it changes how you feel is where the evidence is still thin, and we say so before you spend anything. NAD+ therapy near Leesburg, FL here is a take-home subcutaneous protocol, not an infusion chair, directed by a clinician with a biochemistry background and twenty-two years in The Villages, with a medical doctor on site, and with checkpoints so you are judging real change rather than hoping for it. About twenty minutes north on 27, and only for the consultation.
NAD+ protocols are directed by Dr. Christopher Cheshire, MS, AP, LAc, DOM, with a biochemistry background and 22 years in The Villages. Medical oversight by Dr. Thomas Phipps, MD. Meet the providers
In short: Does NAD+ therapy work? Our NAD+ therapy in Leesburg, FL page says what the trials settle and what they do not, then a take-home plan with a checkpoint. "Does NAD therapy work?" is the question every page selling it should answer first and almost none does.
What The Trials Show
Three things that are settled, and one that is not.
Most clinic pages skip this section. We think it is the page.
Settled: NAD+ falls with age
Levels in tissue decline steadily through adult life, and NAD+ sits at the center of how mitochondria make energy and how cells repair DNA. That is why it appears in every serious longevity conversation and why the fatigue, slower recovery and fog people notice after sixty are plausibly connected to it.
Settled: you can raise it
Human trials of the oral precursors NR and NMN, in middle-aged and older adults, reliably raise blood NAD+ and are well tolerated over weeks to months. A 24-week placebo-controlled trial of high-dose NMN in people over 65 confirmed the rise in blood NAD+ and related metabolites.
Not settled: what you feel
That same 24-week trial did not improve its primary outcome or physical performance measures. A review of ten NMN trials, 437 people, found non-significant changes in physical performance and no serious side effects. A pilot in older adults with mild cognitive impairment raised NAD+ without a significant cognitive change. Injected NAD+ itself has very little controlled trial data at all.
What we do with that
We tell you the above before you start. We screen your fatigue for the causes that are not cellular. We run a defined protocol with checkpoints at a few weeks and again later, judged on your energy, clarity and recovery, and we stop if nothing has changed. That is the honest version of "does it work": for some people, noticeably; for others, not, and we would rather you know which within weeks than pay for months.
The Protocol
Small doses at home, a few times a week.
We do not do NAD+ in the office and we do not do IV drips. You leave with everything you need, shown step by step, to self administer small subcutaneous NAD+ injections at home on your own schedule, the way people take insulin, with a very fine needle. Small doses a few times a week avoid the flushing, nausea and chest tightness that make fast IV infusions unpleasant, and consistency over weeks is what determines the result. It is not a stimulant and the change, if it comes, is gradual. Full NAD+ therapy page.
NAD+ is its own category, distinct from peptide therapy, which sends repair signals to specific tissues; fatigue and fog point to NAD+, an injury that will not heal points to peptides, and slowed recovery with age sometimes benefits from both. It sits inside our functional medicine and healthy aging work alongside a short, specific supplement list rather than a cupboard full.
What To Expect
What happens at the first nad+ therapy visit for Leesburg patients?
A conversation, and a screen
Dr. Cheshire reviews your goals, history, medications and what has already been ruled out. Thyroid, iron, sleep, mood, heart and lung causes of fatigue are not cellular, and if one is more likely we say so and point you there, with Dr. Phipps, MD, in the building.
The take-home set-up
One visit. You leave with the supplies and the technique, and the full protocol cost in writing.
Gradual, consistent dosing
A few small doses a week to start, at home, on your schedule.
Checkpoints
By phone or a follow-up at a few weeks and again later: energy, clarity, recovery, scored against where you started. Then maintenance, a cycle off, or stop because it did not help. The drive is occasional, not weekly.
Cost and Insurance
How much does nad+ therapy cost for Leesburg patients, and what does insurance cover?
What sets the price
A take-home protocol, so you pay for the protocol and supplies rather than chair time in an infusion suite, which makes it considerably less per dose than IV NAD+. The full protocol cost is quoted at the free consultation.
Insurance and Medicare
NAD+ therapy is self pay; we do not bill insurance for it and Medicare does not cover it Source: CMS National Coverage Determination 30.3.3. Acupuncture visits in the same plan are covered by many plans, and we check yours first.
How long it runs
An initial series over several weeks, then maintenance dosing or a cycle off, judged on how energy, clarity and recovery actually change. No subscription.
The first 20 minute consultation is free and no referral is needed. Call 352-430-2720. For reference, consumer cost guides put a single acupuncture visit in the United States at roughly $50 to $150, and we quote your own course in writing at the free consultation. Source: Money.com guide to alternative medicine costs. Insurance and payment details.
Is This You, Leesburg?
Worth trying when:
- Fatigue or fog has persisted despite adequate sleep.
- Standard bloodwork has come back without a clear explanation.
- You are recovering more slowly than you used to.
- You want the evidence stated plainly and a checkpoint, not a subscription.
- You would rather run a protocol at home than sit for infusions.
Not for everyone. Pregnancy, active cancer treatment and some medical conditions call for caution or a different approach, and unexplained fatigue sometimes needs a physician work-up before anything else. We take a careful history first.
Common Questions
What do Leesburg patients ask about nad+ therapy?
Patient Reviews
What patients say on Google.
Dr. Cheshire is rated 4.6 of 5 on Healthgrades from 11 patient ratings as of October 2026 (Healthgrades profile). The quotes above are from Google.
Getting Here From Leesburg
~20 min door to door.
Head north on US 441/27, then take County Road 466 west to Old Camp Road. Free parking right at the door.
Address910 Old Camp Road, Suite 162
The Villages, FL 32162
Phone352-430-2720
HoursMonday to Thursday, 7 AM to 3 PM
Friday, 7 AM to 12 PM
From Leesburg~20 min. Ground floor, step-free entry, free parking. Directions
Many Leesburg patients come to us looking for another option before surgery. The drive is quick, and parking is right at the door.
Nearby Communities We Also See Patients From
Medically Reviewed
Checked by the doctors who treat you
This page was written and reviewed by Dr. Christopher Cheshire, MS, AP, LAc, DOM (NCCAOM board certified). Last reviewed September 2026. Content updated November 3, 2026. Serving Leesburg patients from The Villages.
Educational content only. Not medical advice, diagnosis, or treatment. Results vary between patients and nothing here is a guarantee of outcome.
Further reading: NIH Office of Dietary Supplements: niacin (vitamin B3) fact sheet ยท MedlinePlus: dietary supplements.
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